针对真杆菌属和消化链球菌属菌种的抗体与克罗恩病的估计概率
Antibodies to Eubacterium and Peptostreptococcus species and the estimated probability of Crohn's disease.
作者信息
Van de Merwe J P, Schmitz P I, Wensinck F
出版信息
J Hyg (Lond). 1981 Aug;87(1):25-33. doi: 10.1017/s0022172400069205.
Abstract
Anaerobic coccoid rods belonging to species of Eubacterium and Peptostreptococcus agglutinate more frequently with sera from patients with Crohn's disease than with sera from patients suffering from other diseases and from healthy subjects. Results of agglutination test with four strains of coccoid anaerobes were used to estimate the probability that a patient suffers from Crohn's disease. The data on healthy subjects and patients with Crohn's disease were subjected to logistic discriminant analysis. With the methods and interpretation described, 52% of the patients with Crohn's disease were recognized as 'definite' or 'probable' Crohn's disease and 14% as 'suspected'. Only 1% of the healthy subjects were classified as 'suspected' and non as 'definite' or 'probable' Crohn's disease.
摘要
属于真杆菌属和消化链球菌属的厌氧球状杆菌，与克罗恩病患者血清发生凝集的频率高于与其他疾病患者及健康受试者血清发生凝集的频率。用四株球状厌氧菌进行凝集试验的结果，用于估计患者患克罗恩病的概率。对健康受试者和克罗恩病患者的数据进行了逻辑判别分析。采用所述方法和解释，52%的克罗恩病患者被判定为“确诊”或“可能”患有克罗恩病，14%被判定为“疑似”。只有1%的健康受试者被归类为“疑似”，没有“确诊”或“可能”患有克罗恩病的情况。
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