Narata A P, Arruda W O, Uemura E, Yukita S, Blume A G, Suguiura C, Pedrozo A A
Unidade de Ciências Neurológicas, Hospital das Nações/Hospital Vita, Curitiba, PR.
Arq Neuropsiquiatr. 1998 Jun;56(2):245-9. doi: 10.1590/s0004-282x1998000200013.
Neurocysticercosis (NC) is the most common parasitic disease of the central nervous system and accounts for a significant proportion of morbidity and mortality, in special epilepsy. The authors reviewed 3093 computed tomography scans out of 2554 randomized neurological patients evaluated during a one year period. Most patients (77.3%) were living in Curitiba, Paraná, Brazil. 1821 (58.9%) CT scans were normal. NC was diagnosed in 236 patients based on tomographic criteria; the sex ratio was F:M 1.6:1. 219 (92.8%) patients had the inactive form of NC: 195 (89%) had only isolated intraparenchymal calcifications, and 24 calcifications plus hydrocephalus. Active forms were observed in 14 patients: 8 with degenerating cysts, 4 with viable cysts, 1 with intraventricular cyst, and 1 with racemose form. Three patients had both forms, active (cysts) and inactive (calcifications). The most common clinical finding among patients with tomographic diagnosis of NC was headache alone (35.5%), followed by epilepsy (20.9%). There is a potential role of NC as a causal factor of epilepsy in most of our patients, but surely not in all of them. On the other hand, the finding of inactive NC (calcifications without hydrocephalus and/or meningitic reaction) in patients with headache is probably fortuitous in most cases. In fact, the occasional finding of isolated calcifications in general population is not quite rare, as it was observed in 3.3% of another series of 973 patients with head trauma submitted to CT scan and without epilepsy previous history. The presence of CT findings compatible with NC, especially calcifications, must be carefully correlated with the clinical context in each case. Only then, an unequivocal cause-effect with all its medical and epidemiological implications role can be established.
神经囊尾蚴病(NC)是中枢神经系统最常见的寄生虫病,在发病率和死亡率中占很大比例,尤其是癫痫。作者回顾了在一年期间评估的2554例随机选择的神经科患者中的3093份计算机断层扫描。大多数患者(77.3%)居住在巴西巴拉那州库里蒂巴。1821份(58.9%)CT扫描结果正常。根据断层扫描标准,236例患者被诊断为NC;男女比例为1.6:1。219例(92.8%)患者为非活动性NC:195例(89%)仅有孤立的脑实质内钙化,24例有钙化加脑积水。14例患者观察到活动性形式:8例有退化囊肿,4例有存活囊肿,1例有脑室内囊肿,1例有葡萄状形式。3例患者同时有活动性(囊肿)和非活动性(钙化)两种形式。经断层扫描诊断为NC的患者中最常见的临床发现是单纯头痛(35.5%),其次是癫痫(20.9%)。在我们大多数患者中,NC作为癫痫的病因有潜在作用,但肯定不是所有患者都如此。另一方面,在头痛患者中发现非活动性NC(无脑积水和/或脑膜炎反应的钙化)在大多数情况下可能是偶然的。事实上,在一般人群中偶尔发现孤立钙化并不罕见,在另一组973例有头部外伤且无癫痫病史并接受CT扫描的患者中,观察到这一比例为3.3%。与NC相符的CT表现,尤其是钙化的存在,必须在每种情况下与临床背景仔细关联。只有这样,才能确定其明确的因果关系及其所有医学和流行病学意义。