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儿童神经囊尾蚴病。II. 24例患者根据症状及吡喹酮治疗情况的计算机断层扫描

[Neurocysticercosis in childhood. II. Computed tomography of 24 patients according to symptomatic and praziquantel treatment].

作者信息

Antoniuk S A, Bruck I, Wittig E, Accorsi A

机构信息

Disciplina de Neuropediatria, Universidade Federal do Paraná UFPR, Curitiba, Brasil.

出版信息

Arq Neuropsiquiatr. 1991 Mar;49(1):47-51. doi: 10.1590/s0004-282x1991000100007.

Abstract

We studied 24 children (15 months to 13 years old) which clinical, CSF and CT findings were compatible to the diagnosis of active neurocysticercosis. The patients were divided into three groups based on the type of treatment: Group I (10 patients) treated with analgesics and/or anticonvulsants; Group II (4 patients) treated with analgesics and or anticonvulsants and corticosteroids; Group III (10 patients) treated with analgesics and/or anticonvulsants, corticosteroids and praziquantel. The first patients CT scan were compared with the sequential CT scan findings (1 month to 5 years). The initial CT scan of 12 patients showed multiple active cysts, in 5 patients an isolated active cyst, in 3 patients partial calcified cysts, in 2 patients cerebral edema and in 2 patients were normal. The final results of the three groups of patients, as far as concern the normalization of CSF abnormalities or calcification of the cysts were the same, no matter the type of treatment applied to them. These results, although the small number of patients, showed that most of the children have good final results, with improvement of clinical symptoms and CT findings. We suggest that neurocysticercosis in children need multicenter study. So, a great number of patients can be followed and better definition can be established on the treatment of neurocysticercosis.

摘要

我们研究了24名儿童(年龄在15个月至13岁之间),他们的临床、脑脊液和CT检查结果均符合活动性神经囊尾蚴病的诊断。根据治疗类型将患者分为三组:第一组(10例患者)采用镇痛药和/或抗惊厥药治疗;第二组(4例患者)采用镇痛药和/或抗惊厥药以及皮质类固醇治疗;第三组(10例患者)采用镇痛药和/或抗惊厥药、皮质类固醇以及吡喹酮治疗。将首批患者的CT扫描结果与后续的CT扫描结果(1个月至5年)进行比较。12例患者的初始CT扫描显示有多个活动性囊肿,5例有单个活动性囊肿,3例有部分钙化囊肿,2例有脑水肿,2例正常。就脑脊液异常的正常化或囊肿钙化而言,三组患者的最终结果相同,无论采用何种治疗方式。尽管患者数量较少,但这些结果表明,大多数儿童最终结果良好,临床症状和CT检查结果均有改善。我们建议对儿童神经囊尾蚴病进行多中心研究。这样就能跟踪大量患者,并更好地确定神经囊尾蚴病的治疗方法。

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