Hahn R G
Department of Anaesthesia, Söder Hospital, Stockholm, Sweden.
Eur J Anaesthesiol. 1998 Jul;15(4):427-32. doi: 10.1046/j.1365-2346.1998.00313.x.
Ringer's solution expands blood volume by between 20% and 25% in awake volunteers, but little is known about its volume effect during general anaesthesia. In 35 men with a mean age of 70 years, the power of various intra-operative factors to change blood volume as estimated by the haemoglobin dilution method were analysed by multiple linear regression every 10 min during transurethral resection of the prostate performed under enflurane anaesthesia. The results show that blood volume increased by 60% of the infused Ringer's solution and by 35% of the irrigating fluid absorbed directly into the blood, while it decreased by slightly more than 100% of the bled volume. There was no correlation between systolic pressure and blood volume changes. This suggests that the volume effect of Ringer's solution in the blood is greater than generally believed during general anaesthesia.
林格氏液可使清醒志愿者的血容量增加20%至25%，但对于其在全身麻醉期间的容量效应却知之甚少。在35名平均年龄为70岁的男性患者中，于恩氟烷麻醉下进行经尿道前列腺切除术时，每隔10分钟通过多元线性回归分析各种术中因素通过血红蛋白稀释法估计改变血容量的能力。结果显示，血容量增加了输入林格氏液量的60%以及直接吸收进入血液的灌洗液量的35%，而减少量略超过出血量的100%。收缩压与血容量变化之间无相关性。这表明在全身麻醉期间，林格氏液在血液中的容量效应比一般认为的要大。
