Phillips K A, Gunderson J G, Triebwasser J, Kimble C R, Faedda G, Lyoo I K, Renn J
Personality and Psychosocial Research Program, McLean Hospital, Belmont, Mass, USA.
Am J Psychiatry. 1998 Aug;155(8):1044-8. doi: 10.1176/ajp.155.8.1044.
Depressive personality disorder was introduced into DSM-IV's appendix amid controversy. While that disorder appears to be a reliable and valid one, the authors offer new data about its relationship to major depression, dysthymic disorder, and other personality disorders.
The authors assessed 54 subjects with early-onset, long-standing mild depressive features for depressive personality disorder, axis I and axis II disorders, family history, and treatment history; they conducted follow-up interviews 1 year after the baseline assessment. Subjects with (N=30) and without (N=24) depressive personality disorder were characterized and compared in terms of those variables.
Although depressive personality disorder and dysthymia co-occurred in some subjects, 63% of subjects with depressive personality disorder did not have dysthymia, and 60% did not have current major depression. Although subjects with depressive personality disorder were more likely than the mood disorder comparison group to have another personality disorder, 40% had no such disorder. Contrary to study hypotheses, mood disorder was not more common in first-degree relatives of subjects with depressive personality disorder than in relatives of the comparison group. Subjects with and without depressive personality disorder had similar rates of past treatment with medication and psychotherapy; however, the duration of psychotherapy was significantly longer for subjects with than for those without depressive personality. The depressive personality diagnosis was relatively stable over the 1-year follow-up period.
Depressive personality disorder appears to be a relatively stable condition with incomplete overlap with axis I mood disorders and personality disorders. Further studies are needed to better characterize its treatment response and relationship to axis I mood disorders.
抑郁性人格障碍在争议声中被纳入《精神疾病诊断与统计手册》第四版附录。尽管该障碍似乎是一种可靠且有效的疾病,但作者提供了有关其与重度抑郁症、恶劣心境障碍及其他人格障碍关系的新数据。
作者评估了54名具有早发、长期轻度抑郁特征的受试者,以确定其是否患有抑郁性人格障碍、轴I和轴II障碍、家族史及治疗史;在基线评估1年后进行随访访谈。对患有(N = 30)和未患有(N = 24)抑郁性人格障碍的受试者,就这些变量进行了特征描述和比较。
尽管有些受试者同时患有抑郁性人格障碍和恶劣心境,但63%患有抑郁性人格障碍的受试者没有恶劣心境,60%没有当前的重度抑郁症。尽管患有抑郁性人格障碍的受试者比心境障碍对照组更可能患有另一种人格障碍,但40%的人没有此类障碍。与研究假设相反,抑郁性人格障碍受试者的一级亲属中,心境障碍并不比对照组亲属更常见。患有和未患有抑郁性人格障碍的受试者过去接受药物治疗和心理治疗的比例相似;然而,患有抑郁性人格障碍的受试者接受心理治疗的持续时间明显长于未患该障碍的受试者。在1年的随访期内,抑郁性人格诊断相对稳定。
抑郁性人格障碍似乎是一种相对稳定的状况,与轴I心境障碍和人格障碍的重叠并不完全。需要进一步研究以更好地描述其治疗反应以及与轴I心境障碍的关系。