Cremer H, Koischwitz D
Acta Hepatogastroenterol (Stuttg). 1976 Jul-Aug;23(4):280-7.
The diffuse hypertrophy of the lower esophagus is a hypertrophy and hyperplasia of the smooth muscle fibres of the M. propria, together with a distortion of the muscular architecture. The esophagogram reveals an impaired peristalsis and expansile ability of the esophagus lumen. The focal hypertrophy of the pyloric musculature in adults is a locally circumscribed hypertrophy and hyperplasia of the M. propria. The concentric pattern of the M. propria is no longer maintained. Radiologically one recognizes a benign pylorus stenosis with a complete systole and an impaired diastolic dilatation. On the basis of these macroscopical, microscopical and radiological findings both lesions differ from the circular pyloric or esophageal stenosis which occurs at the same anatomical sites. We therefore feel, that both lesions are different entities.
食管下段弥漫性肥大是固有肌层平滑肌纤维的肥大和增生，同时伴有肌肉结构的扭曲。食管造影显示食管蠕动和管腔扩张能力受损。成人幽门肌层的局灶性肥大是固有肌层的局部局限性肥大和增生。固有肌层的同心模式不再维持。放射学上可识别出良性幽门狭窄，伴有完全收缩和舒张期扩张受损。基于这些宏观、微观和放射学表现，这两种病变均不同于发生在相同解剖部位的环形幽门或食管狭窄。因此，我们认为这两种病变是不同的实体。
