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急性淋巴细胞白血病完全缓解13年后出现睾丸复发。

Testicular relapse after 13 years of complete remission of acute lymphoblastic leukemia.

作者信息

Franck P, Duffner U, Schulze-Seemann W, Riede U, Dördelmann M, Niemeyer C M

机构信息

University Children's Hospital, Department of Urology, Freiburg Medical School, Freiburg, Germany.

出版信息

Urol Int. 1998 Aug;60(4):239-41. doi: 10.1159/000030263.

DOI:10.1159/000030263
PMID:9701738
Abstract

Girls with acute lymphoblastic leukemia appear to have a higher cure rate than boys. This is in part attributable to the reoccurrence of testicular disease in boys. Although the frequency of testicular relapse is less than 5% with current intensive therapy regimens, testicular disease remains of apparent clinical importance. Here we report an unusually late testicular relapse in an 18-year-old male after 12.7 years of continuous complete remission, and review the literature regarding this late failure.

摘要

患急性淋巴细胞白血病的女孩似乎比男孩有更高的治愈率。这部分归因于男孩的睾丸疾病复发。尽管采用目前的强化治疗方案,睾丸复发的频率低于5%,但睾丸疾病在临床上仍具有明显的重要性。在此,我们报告一名18岁男性在持续完全缓解12.7年后出现异常晚发的睾丸复发,并回顾有关这种晚期治疗失败的文献。

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Nat Rev Urol. 2013 Aug;10(8):463-72. doi: 10.1038/nrurol.2013.145. Epub 2013 Jul 9.
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Pediatr Radiol. 2004 May;34(5):400-8. doi: 10.1007/s00247-003-1137-9. Epub 2004 Feb 25.