Vandercam B, Gala J L, Gerain J, Degraux J, Bourlond A, Colebunders B, Pirard C, Portaels F
Department of Clinical Molecular Biology, St-Luc University Hospital Brussels, Belgium.
Acta Clin Belg. 1998 Jun;53(3):206-12.
Mycobacterium simiae is an ubiquitous species rarely involved as a cause of human infection. Its pathogenicity remains therefore unclear and controversial. Disseminated infections with M. simiae occur rarely and only 7 cases have been reported in patients with acquired immunodeficiency syndrome (AIDS). At least, two were mixed infections caused by M. simiae and M. avium-intracellulare. We report the case of two AIDS patients presenting with pure M. simiae infections: one was a disseminated infection and the other a pulmonary infection. Epidemiology and pathogenicity of M. simiae in pulmonary, extra-pulmonary and disseminated infections are reviewed.
猿猴分枝杆菌是一种广泛存在的菌种，很少作为人类感染的病因。因此，其致病性仍不明确且存在争议。猿猴分枝杆菌的播散性感染很少见，获得性免疫缺陷综合征（AIDS）患者中仅报告过7例。其中至少有两例是由猿猴分枝杆菌和鸟分枝杆菌复合群引起的混合感染。我们报告了两例呈现单纯猿猴分枝杆菌感染的艾滋病患者病例：一例为播散性感染，另一例为肺部感染。本文对猿猴分枝杆菌在肺部、肺外及播散性感染中的流行病学和致病性进行了综述。
