Laforga J B, Chordá D, Sevilla F
Department of Pathology, Hospital Marina Alta, Denia, Spain.
Diagn Cytopathol. 1998 Aug;19(2):124-6. doi: 10.1002/(sici)1097-0339(199808)19:2<124::aid-dc12>3.0.co;2-h.
We report on a case of a patient with diagnosis of mycosis fungoides (MF) who subsequently developed enlargement of the intramammary lymph nodes, which were demonstrated to be involved by tumor on fine-needle aspiration (FNA) cytology. The patient was a 66-yr-old female who had recently noticed the appearance of circumscribed bilateral breast nodules. A mammographic study showed clearly outlined nodules of low density. FNA showed atypical small and large lymphocytes with cerebriform appearance, consistent with intramammary lymph node infiltration by MF. To our knowledge this is the first report of intramammary palpable lymph nodes involved by MF and confirmed by FNA. This case provides support for the use of fine-needle aspiration biopsy as an accurate method for staging MF successfully.
我们报告了一例诊断为蕈样肉芽肿（MF）的患者，该患者随后出现乳腺内淋巴结肿大，细针穿刺（FNA）细胞学检查显示肿瘤累及这些淋巴结。患者为一名66岁女性，她最近注意到双侧乳房出现边界清晰的结节。乳腺钼靶检查显示低密度结节轮廓清晰。FNA显示具有脑回样外观的非典型小淋巴细胞和大淋巴细胞，符合MF对乳腺内淋巴结的浸润。据我们所知，这是首例经FNA证实的MF累及可触及乳腺内淋巴结的报告。该病例为将细针穿刺活检作为成功分期MF的准确方法提供了支持。
