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一种用于小规模动物实验的放射性汞蒸气产生与暴露系统。

A radioactive mercury vapor generating and exposing system for small scale animal experiments.

作者信息

Sugata Y, Clarkson T W, Magos L

出版信息

Am Ind Hyg Assoc J. 1976 Aug;37(8):449-52. doi: 10.1080/0002889768507494.

DOI:10.1080/0002889768507494
PMID:970319
Abstract

An apparatus is described for exposing small animals to high specific activity elemental mercury vapor. The vapor is generated by reduction of mercury chloride labelled with the 203HG isotope. The vapor is carried by a constant stream of air into the exposure chamber. The method has been used to expose rats or mice to constant air concentrations of mercury vapor in the range from 0.008 to 0.32 mg/m3. The specific activity of the mercuric chloride used in the study was approximately 1.8 mCi/mgHg. This is sufficiently high to allow measurement of tissue deposition of mercury after an exposure period of only 30 minutes.

摘要

描述了一种用于使小动物暴露于高比活度元素汞蒸气的装置。该蒸气通过还原标记有203HG同位素的氯化汞产生。蒸气由恒定气流带入暴露室。该方法已用于使大鼠或小鼠暴露于0.008至0.32 mg/m3范围内恒定空气浓度的汞蒸气中。该研究中使用的氯化汞的比活度约为1.8 mCi/mgHg。这足够高,以至于仅在暴露30分钟后就可以测量汞在组织中的沉积情况。

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