A cosmid specific for sequences encoding a microtubule-associated protein, MAP1B, contains a polymorphic microsatellite and maps to bovine chromosome 20q14.
作者信息
Eggen A, Solinas-Toldo S, Fries R
机构信息
Swiss Federal Institute of Technology, ETH Zentrum, Zurich, Switzerland.
出版信息
J Hered. 1998 Jul-Aug;89(4):359-63. doi: 10.1093/jhered/89.4.359.
PMID:9703692
Abstract
A clone for the bovine gene MAP1B was isolated from a bovine cosmid library with a probe obtained by cross-species PCR. The single positive cosmid clone was localized by FISH to chromosome region 20q14. Analysis of the cosmid revealed the presence of a microsatellite motif with a two-allele polymorphism detectable by PCR amplification of genomic DNA. However, the analysis of this polymorphism in a bovine family affected by SMA indicated absence of very close linkage of the phenotype for bovine SMA with MAP1B.
摘要
相似文献
1
A cosmid specific for sequences encoding a microtubule-associated protein, MAP1B, contains a polymorphic microsatellite and maps to bovine chromosome 20q14.
J Hered. 1998 Jul-Aug;89(4):359-63. doi: 10.1093/jhered/89.4.359.
2
Fine-mapping of the spinal muscular atrophy locus to a region flanked by MAP1B and D5S6.脊髓性肌萎缩基因座的精细定位至由微管相关蛋白1B（MAP1B）和D5S6侧翼的区域。
Genomics. 1992 Aug;13(4):991-8. doi: 10.1016/0888-7543(92)90012-h.
3
A highly polymorphic bovine dinucleotide repeat D3S40 (IOBT 250) derived from a chimeric cosmid clone.
Anim Genet. 1996 Feb;27(1):59. doi: 10.1111/j.1365-2052.1996.tb01182.x.
4
Physically mapped, cosmid-derived microsatellite markers as anchor loci on bovine chromosomes.经物理定位的、来自黏粒的微卫星标记作为牛染色体上的锚定基因座。
Mamm Genome. 1993 Dec;4(12):720-7. doi: 10.1007/BF00357796.
5
UCD001: a bovine cosmid containing a polymorphic dinucleotide repeat maps to chromosome 4.
Anim Genet. 1995 Oct;26(5):372-3. doi: 10.1111/j.1365-2052.1995.tb02684.x.
6
FBN3 (D6S24): a bovine microsatellite derived from cosmid cIOBT475 at chromosome 6q12-14.FBN3（D6S24）：一种源自6号染色体6q12 - 14区域粘粒cIOBT475的牛微卫星。
Anim Genet. 1996 Feb;27(1):61. doi: 10.1111/j.1365-2052.1996.tb01185.x.
7
Direct characterization of bovine microsatellites from cosmids: polymorphism and synteny mapping.从黏粒中直接鉴定牛微卫星：多态性和同线基因定位
Anim Genet. 1994 Aug;25(4):209-14. doi: 10.1111/j.1365-2052.1994.tb00195.x.
8
Integrating the porcine physical and linkage map using cosmid-derived markers.利用黏粒衍生标记整合猪的物理图谱和连锁图谱。
Anim Genet. 1994 Jun;25(3):155-64. doi: 10.1111/j.1365-2052.1994.tb00104.x.
9
10
Mapping of two new markers within the smallest interval harboring the spinal muscular atrophy locus by family and radiation hybrid analysis.通过家系分析和辐射杂种分析在包含脊髓性肌萎缩症基因座的最小区间内定位两个新标记。
Hum Genet. 1994 May;93(5):494-501. doi: 10.1007/BF00202811.
Zotero 插件