Niinobu T, Shibata T, Shibata N, Takada T, Kitada M, Tsukahara Y, Hata S, Ikeda K, Hayashida H, Ogawa M, Hayashi N, Akazawa K, Takami M
Dept. of Surgery, Toyonaka Municipal Hospital.
Gan To Kagaku Ryoho. 1998 Jul;25(9):1379-81.
A 47-year-old male patient with chronic hepatitis had a high AFP level during the follow-up period. Abdominal CT revealed at S5, which led to a diagnosis of hepatocellular carcinoma. In August 1992, partial resection of S5 was performed, and ethanol was injected into the tumor at S2. In July 1993, recurrent tumors were observed at S5 and S3. PEIT was performed for each lesion. In December 1994, multiple recurrence was observed and 4 mg SMANCS was injected through the proper hepatic artery. In July 1995, another 4 mg of SMANCS was injected into the tumors. In June 1996, only a 20 mm lesion at S5 remained while the other lesions disappeared. Under general anesthesia, the patient underwent percutaneous microwave tumor coagulation. In December 1997, the AFP level was normal, and imaging revealed disappearance of the recurrent tumor. Selection of local therapy for hepatocellular carcinoma achieved long survival in our case considering the QOL and frequent therapy administration.
一名患有慢性肝炎的47岁男性患者在随访期间甲胎蛋白水平较高。腹部CT显示在S5处有病变,从而诊断为肝细胞癌。1992年8月,对S5进行了部分切除,并向S2处的肿瘤注射了乙醇。1993年7月,在S5和S3处观察到复发性肿瘤。对每个病灶进行了经皮乙醇注射治疗(PEIT)。1994年12月,观察到多处复发,并通过肝固有动脉注射了4毫克丝裂霉素明胶微球(SMANCS)。1995年7月,又向肿瘤内注射了4毫克SMANCS。1996年6月,S5处仅残留一个20毫米的病灶,其他病灶消失。在全身麻醉下,患者接受了经皮微波肿瘤凝固治疗。1997年12月,甲胎蛋白水平正常,影像学检查显示复发性肿瘤消失。考虑到生活质量和频繁的治疗,在我们的病例中,肝细胞癌局部治疗的选择实现了长期生存。