Eberle R L, Norris M C, Eberle A M, Naulty J S, Arkoosh V A
Department of Anesthesiology, Albany Medical College, New York 12208-3479, USA.
Am J Obstet Gynecol. 1998 Jul;179(1):150-5. doi: 10.1016/s0002-9378(98)70266-2.
This study was designed to determine the relationship between maternal position and the incidence of prolonged decelerations after epidural bupivacaine or intrathecal sufentanil analgesia for labor.
Laboring, healthy, term parturient women, with reassuring fetal heart rate tracings, requesting either epidural (n = 145) or intrathecal (n = 160) analgesia were randomly assigned to lie either supine with measured 30-degree left uterine displacement (n = 136) or in the left lateral decubitus position (n = 145). Patients received either intrathecal sufentanil, 10 microg, or epidural 0.25% bupivacaine, 13 mL. An obstetrician, unaware of patient position or type of anesthesia, examined the fetal heart rate tracings.
No demographic differences were noted among the groups. Prolonged decelerations occurred with equal frequency after epidural bupivacaine and intrathecal sufentanil (3.9%). Prolonged decelerations were not related to maternal position. No emergency cesarean deliveries were performed as a result of prolonged decelerations. Prolonged decelerations correlated with the frequency of contractions before induction of analgesia (P < .05). Fewer fetal heart rate accelerations were noted after intrathecal sufentanil than after epidural bupivacaine (P < .005). More ephedrine was used after epidural bupivacaine (P < .001). Patients who received epidural analgesia in the left lateral position were more likely to have an asymmetric block (P < .05).
The risk of prolonged deceleration after epidural bupivacaine or intrathecal sufentanil labor analgesia is unrelated to maternal position or analgesic technique.
本研究旨在确定产妇体位与硬膜外布比卡因或鞘内舒芬太尼分娩镇痛后延长减速发生率之间的关系。
待产的健康足月产妇,胎儿心率监测结果令人放心,要求进行硬膜外麻醉(n = 145)或鞘内麻醉(n = 160),被随机分配为仰卧位并测量向左子宫移位30度(n = 136)或左侧卧位(n = 145)。患者接受鞘内舒芬太尼10微克或硬膜外0.25%布比卡因13毫升。一名产科医生在不知道患者体位或麻醉类型的情况下检查胎儿心率监测结果。
各组之间未观察到人口统计学差异。硬膜外布比卡因和鞘内舒芬太尼后延长减速的发生率相同(3.9%)。延长减速与产妇体位无关。没有因延长减速而进行紧急剖宫产。延长减速与镇痛诱导前的宫缩频率相关(P < .05)。鞘内舒芬太尼后观察到的胎儿心率加速比硬膜外布比卡因后少(P < .005)。硬膜外布比卡因后使用麻黄碱更多(P < .001)。左侧卧位接受硬膜外镇痛的患者更有可能出现不对称阻滞(P < .05)。
硬膜外布比卡因或鞘内舒芬太尼分娩镇痛后延长减速的风险与产妇体位或镇痛技术无关。