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溶栓治疗在反常栓塞管理中的作用。

The role of thrombolytic therapy in the management of paradoxical embolism.

作者信息

d'Audiffret A, Shenoy S S, Ricotta J J, Dryjski M

机构信息

Department of Surgery, SUNY at Buffalo, New York, USA.

出版信息

Cardiovasc Surg. 1998 Jun;6(3):302-6. doi: 10.1016/s0967-2109(97)00154-3.

DOI:10.1016/s0967-2109(97)00154-3
PMID:9705104
Abstract

Paradoxical emboli are considered a rare event, representing less than 2% of all arterial emboli. The most common intracardiac defect associated with paradoxical emboli is a patent foramen ovale. Most commonly, a pulmonary embolism is the cause of the acute increase in right atrial pressure leading to a reversal of intracardiac flow and passage of venous embolic material to the left heart. We present a patient with a pulmonary embolism and paradoxical emboli, and discuss therapeutic approach. We suggest that the treatment of choice for the patient with pulmonary embolism and non-limb-threatening acute ischemia due to a paradoxical emboli should be thrombolytic therapy and intracaval filter placement, followed by patent foramen ovale repair.

摘要

反常栓塞被认为是一种罕见事件,占所有动脉栓塞的比例不到2%。与反常栓塞相关的最常见心脏内缺损是卵圆孔未闭。最常见的情况是,肺栓塞是右心房压力急性升高的原因,导致心内血流逆转以及静脉栓子物质进入左心。我们报告一例患有肺栓塞和反常栓塞的患者,并讨论治疗方法。我们建议,对于因反常栓塞导致肺栓塞和非肢体威胁性急性缺血的患者,治疗选择应为溶栓治疗和下腔静脉滤器置入,随后进行卵圆孔未闭修复。

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1
The role of thrombolytic therapy in the management of paradoxical embolism.溶栓治疗在反常栓塞管理中的作用。
Cardiovasc Surg. 1998 Jun;6(3):302-6. doi: 10.1016/s0967-2109(97)00154-3.
2
Paradoxical embolism and acute arterial occlusion: rare or unsuspected?反常栓塞与急性动脉闭塞:罕见还是未被察觉?
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Impending paradoxical embolism across a patent foramen ovale: case report.卵圆孔未闭导致的即将发生的反常栓塞:病例报告
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Paradoxical peripheral embolism coincident with acute pulmonary thromboembolism.矛盾性外周栓塞与急性肺血栓栓塞同时发生。
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Spontaneous closure of a patent foramen ovale and disappearance of impending paradoxical embolism after fibrinolytic therapy in the course of massive pulmonary embolism.
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Submassive pulmonary embolism and paradoxical embolic stroke treated with percutaneous rheolytic thrombectomy and closure of the patent foramen ovale.经皮血栓溶解切除术及卵圆孔未闭封堵术治疗亚大面积肺栓塞和反常栓塞性卒中
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[Paradoxical embolism after thrombolytic treatment in a patient with pulmonary embolism and right atrial thrombus].[一名患有肺栓塞和右心房血栓的患者在溶栓治疗后发生反常栓塞]
Anadolu Kardiyol Derg. 2007 Dec 8;7(4):E6.

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