一名16岁男孩患免疫增殖性小肠疾病，表现为严重吸收不良，对四环素治疗反应良好。

Immunoproliferative small intestinal disease in a 16-year-old boy presenting as severe malabsorption with excellent response to tetracycline treatment.

作者信息

Zamir A, Parasher G, Moukarzel A A, Guarini L, Zeien L, Feldman F

机构信息

Department of Gastroenterology, Maimonides Medical Center, Brooklyn, NY 11219, USA.

出版信息

J Clin Gastroenterol. 1998 Jul;27(1):85-9. doi: 10.1097/00004836-199807000-00020.

DOI:10.1097/00004836-199807000-00020

PMID:9706780

Abstract

Immunoproliferative small intestinal disease (IPSID) is a rare lympho-proliferative disorder of the upper small intestine. It is considered a special form of MALT lymphoma with propensity to malignant transformation. This disorder is rare in pediatric literature. We report a case of IPSID in a 16-year-old boy with low-grade malignant transformation, presenting as severe malnutrition and a possible association with Helicobacter pylori. The patient responded well to an extended treatment with tetracycline and eradication of H. pylori.

摘要

免疫增殖性小肠疾病（IPSID）是一种罕见的上小肠淋巴增殖性疾病。它被认为是黏膜相关淋巴组织淋巴瘤的一种特殊形式，有恶变倾向。这种疾病在儿科文献中较为罕见。我们报告一例16岁男孩患IPSID并伴有低度恶变，表现为严重营养不良，且可能与幽门螺杆菌有关。该患者对四环素的长期治疗及幽门螺杆菌的根除反应良好。