Woo J I, Lee J H, Yoo K Y, Kim C Y, Kim Y I, Shin Y S
Department of Neuropsychiatry, Seoul National University College of Medicine, Korea.
J Am Geriatr Soc. 1998 Aug;46(8):983-7. doi: 10.1111/j.1532-5415.1998.tb02753.x.
A cross-sectional survey was conducted to estimate prevalence of dementia and to determine factors related to dementia among residents in a rural area, Yonchon county, Korea, in 1993.
Of the study population more than 65 years of age (n = 2171), 1674 persons participated in the cross-sectional survey using the Korean version of the Mini-Mental State Examination (MMSE-K).
Subjects were defined as having dementia according to NINCDS-ADRDA criteria through direct interview by psychiatrists. A total of 436 subjects were selected randomly according to MMSE-K scores, and cases were confirmed as having either Alzheimer's or vascular dementia.
The adjusted prevalence of dementia was estimated at 9.5%. The prevalence of total dementia was 8.8% for men and 9.9% for women. The prevalence of Alzheimer's disease was 3.2% for men and 5.3% for women and that of vascular dementia 3.1% and 2.1%, respectively. Age-standardized prevalence of Alzheimer's disease was 4.5%, whereas that of vascular dementia was 2.5%. Using DSM-III-R criteria to stratify dementia patients according to severity showed the prevalence of mild, moderate, and severe Alzheimer's disease was 3.4%, 0.7%, and 0.5%, respectively.
These results showed that the prevalence of dementia in Korea was similar to its presence in Western countries but different from that previously reported in other Asian countries, e.g., China and Japan.
1993年在韩国延川郡的一个农村地区开展了一项横断面调查，以估计痴呆症的患病率，并确定与痴呆症相关的因素。
在年龄超过65岁的研究人群（n = 2171）中，1674人使用韩国版简易精神状态检查表（MMSE-K）参与了横断面调查。
通过精神科医生直接访谈，根据美国国立神经疾病与中风研究所-阿尔茨海默病及相关疾病协会（NINCDS-ADRDA）标准将受试者定义为患有痴呆症。根据MMSE-K分数随机选择了436名受试者，并确诊病例患有阿尔茨海默病或血管性痴呆。
痴呆症的校正患病率估计为9.5%。男性总痴呆症患病率为8.8%，女性为9.9%。男性阿尔茨海默病患病率为3.2%，女性为5.3%；血管性痴呆患病率分别为3.1%和2.1%。阿尔茨海默病的年龄标准化患病率为4.5%，而血管性痴呆为2.5%。使用《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）标准根据严重程度对痴呆症患者进行分层，结果显示轻度、中度和重度阿尔茨海默病的患病率分别为3.4%、0.7%和0.5%。
这些结果表明，韩国痴呆症的患病率与西方国家相似，但与之前在中国和日本等其他亚洲国家报道的情况不同。
