Izumi C, Inoko M, Kitaguchi S, Himura Y, Iga K, Gen H, Konishi T
Department of Cardiology, Tenri Hospital, Tenri-city, Nara, Japan.
Jpn Circ J. 1998 Jul;62(7):543-5. doi: 10.1253/jcj.62.543.
We describe a 60-year-old patient with adrenal insufficiency and hypothyroidism who experienced syncope as a result of polymorphic ventricular tachycardia associated with long QT intervals. The deep inverted T waves and long QT intervals were normalized about 8 weeks after starting steroid replacement therapy. Although there have been some reports on electrocardiographic abnormality or polymorphic ventricular tachycardia in patients with adrenal insufficiency, the pathogenesis remains unknown. Hormonal disorders should be considered as a cause of polymorphic ventricular tachycardia associated with long QT intervals, even if plasma electrolyte levels are normal, because life-threatening arrhythmia is treatable by supplementation of the hormone that is lacking.
我们描述了一位60岁患有肾上腺功能不全和甲状腺功能减退的患者，该患者因多形性室性心动过速伴长QT间期而发生晕厥。在开始类固醇替代治疗约8周后，深倒置T波和长QT间期恢复正常。尽管已有一些关于肾上腺功能不全患者心电图异常或多形性室性心动过速的报道，但其发病机制仍不清楚。即使血浆电解质水平正常，激素紊乱也应被视为多形性室性心动过速伴长QT间期的一个原因，因为危及生命的心律失常可通过补充缺乏的激素来治疗。
