Martínez Subias J, Domínguez Ugidos L J, Urpegui García A, Sancho Serrano E, Abenia Ingalaturre J M, Millán Guevara J, Valles Varela H
Servicio de ORL, Hospital Clínico Universitario Lozano Blesa, Zaragoza.
Acta Otorrinolaringol Esp. 1998 May;49(4):293-6.
Esthesioneuroblastomas are fairly rare malignant tumors: only 20 cases have been reported in Spanish records. It is locally aggressive and produces late recurrences. There is no such thing as a universally accepted treatment model. We describe our experience with 7 cases seen in our hospital from 1980 to 1996. A or B stages can be treated with irradiation, surgery or a combination of both. C stages with the most aggressive tendencies may require the combined use of preoperative irradiation, surgery and chemotherapy. We analyzed the forms of presentation, diagnosis, differential diagnosis, treatment, prognosis, and survival. The 5-year survival rate was 75, 60 and 41% for stages A, B and C, respectively.
西班牙的记录中仅报告了20例。它具有局部侵袭性，且易出现晚期复发。目前尚无普遍接受的治疗模式。我们描述了1980年至1996年在我院诊治的7例病例的经验。A期或B期可采用放疗、手术或两者联合治疗。具有最具侵袭性倾向的C期可能需要术前放疗、手术和化疗联合应用。我们分析了其临床表现、诊断、鉴别诊断、治疗、预后和生存率。A、B和C期的5年生存率分别为75%、60%和41%。
