Ruiz Gómez J M, Fernández-Cervilla F, Padilla J F, Vergara E
Servicio de ORL, Hospital Universitario de Granada.
Acta Otorrinolaringol Esp. 1998 May;49(4):317-20.
Teratomas are the most common congenital tumors, but neoplasms of the nasopharynx are rare in neonates. The exact origin of teratomas is unknown and debated. Several theories of embryogenesis are possible. These neoplasms include elements from all three germinal layers (endoderm, mesoderm, and ectoderm). Four histological types of nasopharyngeal teratoma occur. We report three cases of dermoid teratoma. All the patients were siblings and two were twins. A review of several large series of pediatric teratomas confirmed the rarity of this site. The classification, clinical features, differential diagnosis and treatment are reviewed.
畸胎瘤是最常见的先天性肿瘤,但新生儿鼻咽部肿瘤罕见。畸胎瘤的确切起源尚不清楚且存在争议。几种胚胎发生理论都是有可能的。这些肿瘤包含来自所有三个胚层(内胚层、中胚层和外胚层)的成分。鼻咽部畸胎瘤有四种组织学类型。我们报告三例皮样畸胎瘤病例。所有患者均为兄弟姐妹,其中两例为双胞胎。对几大系列小儿畸胎瘤的回顾证实了该部位肿瘤的罕见性。本文对其分类、临床特征、鉴别诊断及治疗进行了综述。