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系统性红斑狼疮所致急性横贯性脊髓炎:一例快速诊断与完全康复的病例

Acute transverse myelitis in systemic lupus erythematosus: a case of rapid diagnosis and complete recovery.

作者信息

Habr F, Wu B

机构信息

Department of Medicine, Hospital of Saint Raphael, New Haven, USA.

出版信息

Conn Med. 1998 Jul;62(7):387-90.

PMID:9707792
Abstract

Acute transverse myelitis is a rare and serious complication of systemic lupus erythematosus. Delay in diagnosis and treatment is associated with significant morbidity and mortality. Earlier diagnosis is facilitated by magnetic resonance imaging. Treatment of systemic lupus erythematosus-related acute transverse myelitis remains controversial. The use of steroids alone may result in incomplete recovery. We report a patient who was promptly diagnosed with systemic lupus erythematosus-related acute transverse myelitis by magnetic resonance imaging. The patient had complete resolution of her symptoms following aggressive treatment with steroids and cyclophosphamide. Review of published treatment of systemic lupus erythematosus-related acute transverse myelitis suggests aggressive therapy with steroids and cyclophosphamide may provide the best outcome.

摘要

急性横贯性脊髓炎是系统性红斑狼疮一种罕见且严重的并发症。诊断和治疗的延迟与显著的发病率和死亡率相关。磁共振成像有助于早期诊断。系统性红斑狼疮相关急性横贯性脊髓炎的治疗仍存在争议。单独使用类固醇可能导致恢复不完全。我们报告一例通过磁共振成像迅速诊断为系统性红斑狼疮相关急性横贯性脊髓炎的患者。该患者在接受类固醇和环磷酰胺积极治疗后症状完全缓解。对已发表的系统性红斑狼疮相关急性横贯性脊髓炎治疗方法的回顾表明,使用类固醇和环磷酰胺进行积极治疗可能会带来最佳结果。

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