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[喂食含不同碳水化合物日粮的大鼠肠道蔗糖酶的反应及生理变化]

[Responses and physiological modifications of intestinal sucrase in rats fed diets containing various carbohydrates].

作者信息

Hoang-Huan P, Hung L V

出版信息

Ann Nutr Aliment. 1976;29(5):395-410.

PMID:970835
Abstract

Weaning rats were submitted during 3 months to complet and balanced diets where only glucidic constituent varied. They were sacrified when fed or after 16 h fasting. 1. The value of intestinal sucrose K(M) is higher in rats fed on glucose dietary than in rats fed on sucrose, fructose or glucose + fructose dietary. These modifications are independant of the states of digestion. 2. The V(MAX) is diversely influenced by the states of digestion: hydric diet increases the V(MAX) in animals fed on sucrose diet when intestinal repletion has the same effect in animals receiving glucose diet. Fructose diet decreases it irreversibility in both cases. 3. Growth of animals is sagging respectively in order from sucrose and glucose diets to glucose + fructose and fructose diets, then weight of organes is unaffected. It was noted that perirenal and epididymal fats are more abundant in rats nourished with glucose diet than with fructose diet. 4. The glucoregulation is correctly effectued in either starved or fed animals and shows an available adaptation of organism in energetic utilisation of various studied sugars. Plasmatic, hepatis and intestinal free fatty acids levels are constant and equal in all series of expements in spite of important variations of reverse fat.

摘要

断奶大鼠在3个月内食用完全且均衡的饮食,仅碳水化合物成分有所不同。喂食时或禁食16小时后将它们处死。1. 以葡萄糖饮食喂养的大鼠肠道蔗糖K(M)值高于以蔗糖、果糖或葡萄糖+果糖饮食喂养的大鼠。这些变化与消化状态无关。2. V(MAX)受消化状态的不同影响:在肠道充盈对接受葡萄糖饮食的动物有相同作用时,水合饮食会增加以蔗糖饮食喂养的动物的V(MAX)。在两种情况下,果糖饮食都会不可逆地降低它。3. 动物的生长分别从蔗糖和葡萄糖饮食到葡萄糖+果糖和果糖饮食依次下降,然后器官重量不受影响。值得注意的是,与果糖饮食相比,以葡萄糖饮食喂养的大鼠肾周和附睾脂肪更丰富。4. 在饥饿或喂食的动物中,葡萄糖调节都能正确进行,并显示出机体在对各种研究糖类的能量利用方面具有有效的适应性。尽管反向脂肪有重要变化,但在所有系列实验中,血浆、肝脏和肠道游离脂肪酸水平都是恒定且相等的。

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1
[Responses and physiological modifications of intestinal sucrase in rats fed diets containing various carbohydrates].[喂食含不同碳水化合物日粮的大鼠肠道蔗糖酶的反应及生理变化]
Ann Nutr Aliment. 1976;29(5):395-410.
2
[Lipid metabolism in rats fed a diet rich in various carbohydrates. I. Results after I.P. injection of lipogenic precursors].[喂食富含各种碳水化合物饮食的大鼠的脂质代谢。I. 腹腔注射生脂前体后的结果]
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J Clin Invest. 1968 Oct;47(10):2253-62. doi: 10.1172/JCI105910.
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