经阴道超声测量早孕期胎儿双顶径/肾长比值作为肾畸形筛查工具的研究
Transvaginal sonographic fetal biparietal diameter/kidney length ratio in early pregnancy as a screening tool for renal malformations.
作者信息
Guariglia L, Rosati P
机构信息
Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
出版信息
Fetal Diagn Ther. 1998 May-Jun;13(3):154-6. doi: 10.1159/000020828.
OBJECTIVE
The aim of the study was to produce by 7.0 MHz high resolution transvaginal scan early in pregnancy normal values of biparietal diameter/kidney length ratio that can be used as reference ranges.
METHODS
In this prospective cross-sectional study, a transvaginal high-resolution sonography was performed between 11 and 16 weeks' gestation in 807 pregnant women with a history of regular cycles, singleton pregnancies and absence of fetal malformations. Measurements of kidney length and biparietal diameter were obtained in all cases and biparietal diameter/kidney length ratio was plotted against gestational age.
RESULTS
The values of biparietal diameter/kidney length ratio were found to be fairly constant throughout the period evaluated.
CONCLUSION
Our results indicate that this new age-independent ratio can be useful in the early detection of some fetal kidney malformations affecting normal growth.
目的
本研究的目的是通过7.0兆赫高分辨率经阴道扫描得出妊娠早期双顶径/肾长比值的正常值，用作参考范围。
方法
在这项前瞻性横断面研究中，对807名月经周期规律、单胎妊娠且无胎儿畸形的孕妇在妊娠11至16周期间进行经阴道高分辨率超声检查。所有病例均测量肾长和双顶径，并绘制双顶径/肾长比值与孕周的关系图。
结果
在评估期间，双顶径/肾长比值相当稳定。
结论
我们的结果表明，这种新的不依赖孕周的比值有助于早期发现一些影响正常生长的胎儿肾脏畸形。
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