Abbott J F, Levine D, Wapner R
Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass 02215, USA.
Fetal Diagn Ther. 1998 May-Jun;13(3):179-83. doi: 10.1159/000020834.
This study was undertaken to determine the specificity of prenatal diagnosis of posterior urethral valves. Twenty-two fetuses were diagnosed in utero with posterior urethral valves due to the presence of persistent megacystis and hydronephrosis. Ten cases had oligohydramnios and 12 had normal or increased fluid. Confirmation of diagnosis was not available in 3 fetuses. Only 8 of 19 fetuses had postnatal confirmation of posterior urethral valves. Other anomalies included urethral atresia, ureteral duplication, megacystis/megaureter, reflux and multicystic dysplastic kidney. We conclude that in utero evidence of megacystis and hydronephrosis with or without oligohydramnios is not diagnostic of posterior urethral valves.
本研究旨在确定后尿道瓣膜产前诊断的特异性。22例胎儿因持续性巨膀胱和肾积水在子宫内被诊断为后尿道瓣膜。10例羊水过少，12例羊水正常或增多。3例胎儿未得到诊断确认。19例胎儿中只有8例产后确诊为后尿道瓣膜。其他异常包括尿道闭锁、输尿管重复、巨膀胱/巨输尿管、反流和多囊性发育不良肾。我们得出结论，子宫内有或无羊水过少的巨膀胱和肾积水证据并不能诊断后尿道瓣膜。
