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[经鼻内放射治疗的遗传性出血性毛细血管扩张症(62例评估)]

[Rendu-Osler disease treated by endonasal radiotherapy (evaluation of 62 cases)].

作者信息

Maylin C, Sauvage J P, Baillet F, Chassagne D, Pierquin B

出版信息

Ann Otolaryngol Chir Cervicofac. 1976 Jan-Feb;93(1-2):95-102.

PMID:970864
Abstract

Two groups of patients were treated by plesiocurietherapy. The first group of 17 patients received only one exposure to radium (between 1949 and 1960). The second group received one or more doses of irridium 192 (between 1960 and 1973). The average period for stabilization of the disease was 13,2 months with radium and 20,4 months with irridium. Unfortunately, this does not give a permanent cure and, for irridium 192, the percentage of successes is only 30 p. 100 after 5 years. Logically, radiotherapy with irridium 192 should only be used when other methods have failed. The progressive accumulation of radio-lesions may, in fact, make the use of other techniques impossible.

摘要

两组患者接受了近距离放射治疗。第一组17名患者仅接受了一次镭照射(1949年至1960年间)。第二组接受了一剂或多剂铱192(1960年至1973年间)。疾病稳定的平均时间,镭治疗为13.2个月,铱治疗为20.4个月。不幸的是,这并不能实现永久治愈,对于铱192来说,5年后的成功率仅为30%。从逻辑上讲,只有在其他方法都失败时才应使用铱192进行放射治疗。事实上,放射性损伤的逐渐累积可能会使其他技术无法使用。

相似文献

1
[Rendu-Osler disease treated by endonasal radiotherapy (evaluation of 62 cases)].[经鼻内放射治疗的遗传性出血性毛细血管扩张症(62例评估)]
Ann Otolaryngol Chir Cervicofac. 1976 Jan-Feb;93(1-2):95-102.
2
[Endonasal contact radiotherapy of Rendu-Osler diseases with iridium-192].[铱-192对遗传性出血性毛细血管扩张症的鼻内接触放疗]
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引用本文的文献

1
[Haemorrhage and haemostasis in face, visceral cranium, neck and middle ear region (author's transl)].面部、面颅骨、颈部及中耳区域的出血与止血(作者译)
Arch Otorhinolaryngol. 1978 Apr 20;219(1):209-83. doi: 10.1007/BF00456579.