通过注射异戊巴比妥和电干扰揭示的右半球言语感知
Right hemisphere speech perception revealed by amobarbital injection and electrical interference.
作者信息
Boatman D, Hart J, Lesser R P, Honeycutt N, Anderson N B, Miglioretti D, Gordon B
机构信息
Department of Neurology, Krieger Mind/Brain Institute, The Johns Hopkins University, Baltimore, MD, USA.
出版信息
Neurology. 1998 Aug;51(2):458-64. doi: 10.1212/wnl.51.2.458.
OBJECTIVE
To investigate the right hemispheric speech perception capabilities of an adult right-handed patient with seizures.
METHODS
Consecutive, unilateral, intracarotid sodium amobarbital injections and left hemispheric electrical interference mapping were used to determine lateralization and localization of speech perception, measured as syllable discrimination.
RESULTS
Syllable discrimination remained intact after left and right intracarotid sodium amobarbital injections. Language otherwise strongly lateralized to the left hemisphere. Despite evidence of bilateral speech perception capabilities, electrical interference testing in the left posterior temporal lobe impaired syllable discrimination.
CONCLUSIONS
The results suggest a functionally symmetric, parallel system in the adult brain with preferential use of left hemispheric pathways for speech perception.
目的
研究一名患有癫痫的成年右利手患者的右半球言语感知能力。
方法
采用连续、单侧、颈内动脉注射戊巴比妥钠以及左半球电干扰图谱法来确定言语感知的定位和定侧，以音节辨别作为衡量指标。
结果
左右颈内动脉注射戊巴比妥钠后，音节辨别能力保持完好。语言功能在其他方面强烈定位于左半球。尽管有证据表明存在双侧言语感知能力，但左后颞叶的电干扰测试损害了音节辨别能力。
结论
结果表明，成人大脑中存在一个功能对称的平行系统，在言语感知方面优先使用左半球通路。
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