Pehrson B, Svensson C, Jonsson M
Department of Animal Environment and Health, Swedish University of Agricultural Sciences, Skara, Sweden.
J Dairy Sci. 1998 Jul;81(7):2011-6. doi: 10.3168/jds.S0022-0302(98)75775-3.
The efficacy of calcium propionate for the prevention of parturient paresis (milk fever) was compared with that of calcium chloride using 194 cows that had experienced milk fever during the previous calving. The cows were mainly of the Swedish Red and White and Swedish Friesian breeds and were divided randomly into an experimental group (n = 99) and a control group (n = 95). The cows in the experimental group received up to six boluses of 20 g of calcium as calcium propionate between 36 h before and 24 h after calving; the cows in the control group received up to four doses of 54 g of calcium as a commercially available oily solution of calcium chloride during the same period. Incidence of milk fever was recorded as the percentage of cows that were treated by a veterinarian because they showed clinical signs of the disease and had a blood calcium concentration less than 8.0 mg/dl. Twenty-five (25.3%) cows in the experimental group and 22 cows (23.2%) in the control group developed milk fever. The incidence of milk fever for cows in both groups was significantly lower than the 36.0% found in 713 cows that had experienced milk fever during their previous calving but received no prophylactic treatment. Therefore, calcium propionate was considered to have had a significant preventive effect, comparable with that of calcium chloride.
使用194头在前次产犊时曾患产乳热的奶牛，比较了丙酸钙与氯化钙预防产乳热（乳热症）的效果。这些奶牛主要是瑞典红白奶牛和瑞典弗里生奶牛品种，被随机分为实验组（n = 99）和对照组（n = 95）。实验组的奶牛在产犊前36小时至产后24小时期间，最多接受6次剂量为20克钙的丙酸钙大丸剂；对照组的奶牛在同一时期，最多接受4次剂量为54克钙的市售氯化钙油溶液。产乳热的发病率记录为因出现该病临床症状且血钙浓度低于8.0毫克/分升而由兽医治疗的奶牛的百分比。实验组中有25头（25.3%）奶牛患产乳热，对照组中有22头（23.2%）奶牛患产乳热。两组奶牛的产乳热发病率均显著低于713头在前次产犊时曾患产乳热但未接受预防性治疗的奶牛中36.0%的发病率。因此，认为丙酸钙具有显著的预防效果，与氯化钙相当。
