Valenzuela García L F, Vázquez García R, Pastor Morales L, Calvo Jambrina R, Rodríguez Hernández M J, Font Cabrera I, Cubero García J, Pastor Torres L, Cruz Fernández J M, Infantes Alcón C
Servicio de Cardiología, Hospital Universitario Virgen Macarena, Sevilla.
Rev Esp Cardiol. 1998 Jul;51(7):572-81.
To analyse the anatomo-clinical characteristics of the coarctation of the aorta at different ages of presentation as well as the findings and results of its surgical correction at different periods.
We retrospectively studied the clinical and angiographic data, as well as the intraoperative findings and surgical outcomes of 82 consecutive patients (54 M and 28 F) with coarctation of the aorta. Mean age was 16.2 +/- 13.7 years (1 month to 63 years). The patients were divided into three groups according to age: Group A (n = 10) under 1 year; Group B (n = 30) from 1 to 12 years and Group C (n = 42) over 12 years.
A preductal form was found in 20.7% cases (50.0%, 30.0% and 7.1% of groups A, B, and C respectively; p = 0.003). An associated left-to-right shunt was present in 19.5% (40.0%, 16.7% and 16.7% of groups A, B and C respectively; p = NS). The first manifestation of the disease was different in groups A, B and C. Among group A patients, congestive heart failure was the most frequent presentation (70.0%). In group B, the most frequent presentation (30%) was as an incidental finding in an asymptomatic patient. Finally, systemic hypertension or its complications predominated among group C patients (38.0%). Left ventricular hypertrophy on ECG was present in 0.0%, 30.0% and 54.7% of patients in groups A, B and C (p = 0.003) respectively. Postoperative complications including death, hypertensive crisis and re-coarctation were observed in 90.0%, 33.3% and 21.4% in groups A, B and C (p = 0.01) respectively.
Among patients with coarctation of the aorta, the age of clinical presentation allows us to define groups of patients with different anatomical characteristics, clinical course and postoperative outcome.
分析不同发病年龄的主动脉缩窄的解剖学临床特征,以及不同时期手术矫正的发现和结果。
我们回顾性研究了82例连续的主动脉缩窄患者(54例男性和28例女性)的临床和血管造影数据,以及术中发现和手术结果。平均年龄为16.2±13.7岁(1个月至63岁)。根据年龄将患者分为三组:A组(n = 10)年龄小于1岁;B组(n = 30)年龄在1至12岁之间;C组(n = 42)年龄超过12岁。
20.7%的病例发现为动脉导管前型(分别占A、B、C组的50.0%、30.0%和7.1%;p = 0.003)。19.5%的患者存在相关的左向右分流(分别占A、B、C组的40.0%、16.7%和16.7%;p = 无显著性差异)。A、B、C组疾病的首发表现不同。在A组患者中,充血性心力衰竭是最常见的表现(70.0%)。在B组中,最常见的表现(30%)是在无症状患者中偶然发现。最后,C组患者中以系统性高血压或其并发症为主(38.0%)。A、B、C组患者心电图显示左心室肥厚的比例分别为0.0%、30.0%和54.7%(p = 0.003)。A、B、C组术后并发症包括死亡、高血压危象和再缩窄的发生率分别为90.0%、33.3%和21.4%(p = 0.01)。
在主动脉缩窄患者中,临床表现的年龄使我们能够定义具有不同解剖特征、临床过程和术后结果的患者群体。