Horner R D
Durham VA Medical Center, Division of General Internal Medicine, NC, USA.
Cancer Treat Res. 1998;97:99-114. doi: 10.1007/978-0-585-30498-4_8.
Prostate cancer is one of several cancers that affects U.S. racial and ethnic groups differently with Blacks experiencing a higher incidence and mortality rate than Whites. Observational studies indicate that black patients with prostate cancer are less likely to receive definitive therapy. This pattern of care appears to be attributable primarily to the later clinical stage of disease at presentation; socioeconomic considerations as such relate to access to care (e.g., ability to pay) appear to play a lesser role. Other patient related factors, for example, preferences for certain therapies, have not been well studied; consequently, their ability to explain racial variations in use of therapies for this disease is unclear. Potential areas for future research should focus on the reasons for the detection of the disease at a later clinical stage and, hence, with worse prognosis.
前列腺癌是几种对美国不同种族和族裔群体有不同影响的癌症之一,黑人的发病率和死亡率高于白人。观察性研究表明,患有前列腺癌的黑人患者接受确定性治疗的可能性较小。这种治疗模式似乎主要归因于疾病呈现时的临床阶段较晚;诸如与获得医疗服务相关的社会经济因素(如支付能力)似乎起到的作用较小。其他与患者相关的因素,例如对某些治疗方法的偏好,尚未得到充分研究;因此,它们能否解释这种疾病治疗方法使用上的种族差异尚不清楚。未来研究的潜在领域应聚焦于在临床阶段较晚时才检测出疾病的原因,从而聚焦于预后较差的原因。