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Amplification of ABC transporter gene pgpA and of other heavy metal resistance genes in Leishmania tarentolae and their study by gene transfection and gene disruption.

作者信息

Ouellette M, Haimeur A, Grondin K, Légaré D, Papadopoulou B

机构信息

Department of Microbiology, Université Laval, Québec, Canada.

出版信息

Methods Enzymol. 1998;292:182-93. doi: 10.1016/s0076-6879(98)92015-8.

DOI:10.1016/s0076-6879(98)92015-8
PMID:9711554
Abstract
摘要

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Amplification of ABC transporter gene pgpA and of other heavy metal resistance genes in Leishmania tarentolae and their study by gene transfection and gene disruption.利什曼原虫中ABC转运蛋白基因pgpA及其他重金属抗性基因的扩增及其通过基因转染和基因敲除的研究
Methods Enzymol. 1998;292:182-93. doi: 10.1016/s0076-6879(98)92015-8.
2
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Structural and functional analysis of an amplification containing a PGPA gene in a glucantime-resistant Leishmania (Viannia) guyanensis cell line.对一株抗葡聚糖胺的圭亚那利什曼原虫(维扬尼亚利什曼原虫)细胞系中包含PGPA基因的扩增片段进行结构和功能分析。
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The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase.利什曼原虫ATP结合盒蛋白PGPA是一种细胞内金属硫醇转运ATP酶。
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