Dallenbach-Hellweg G, Wittlinger H
Beitr Pathol. 1976 Aug;158(3):307-14.
On curettage, done in a 39 year old patient because of metorrhagia, a peanut-sized nodule was scraped away from the endometrium. Histologically it consisted of a jumble of irregularly shaped portions of normal appearing embryonal cartilage, of tortuous thick-walled vessels, of twisted bundles of nerves of ducts of respiratory and intestinal epithelium, and of sheets of hornifying skin. The haphazard disarray of tissues supported the notion that the lesion was not a remnant of a malformed embryo. Step-sections through the lesion revealed no traces of placental villi or decidua in the surrounding endometrium. The following were considered as possible origins of the teratoma: 1. displaced germinal cells, 2. retention of pluripotent müllerian epithelium, 3. overaged or blighted ovum. The latter seems most compatible with the histological findings.
在对一名39岁因子宫出血而行刮宫术的患者进行刮宫时，从子宫内膜刮出一个花生大小的结节。组织学检查显示，它由杂乱的、形状不规则的正常胚胎软骨部分、迂曲的厚壁血管、扭曲的神经束、呼吸和肠上皮导管以及角化皮肤片组成。组织的杂乱排列支持了该病变并非畸形胚胎残余的观点。对病变进行连续切片检查，未在周围子宫内膜中发现胎盘绒毛或蜕膜的痕迹。以下被认为是畸胎瘤的可能起源：1. 移位的生殖细胞；2. 多能苗勒上皮的保留；3. 过熟或枯萎的卵子。后者似乎与组织学发现最为相符。
