Lane R D, Reiman E M, Axelrod B, Yun L S, Holmes A, Schwartz G E
University of Arizona, Department of Psychiatry, Tucson AZ 85724-5002, USA.
J Cogn Neurosci. 1998 Jul;10(4):525-35. doi: 10.1162/089892998562924.
Recent functional imaging studies have begun to identify the neural correlates of emotion in healthy volunteers. However, studies to date have not differentially addressed the brain areas associated with the perception, experience, or expression of emotion during emotional arousal. To explore the neural correlates of emotional experience, we used positron emission tomography (PET) and 15-water to measure cerebral blood flow (CBF) in 12 healthy women during film- and recall-induced emotion and correlated CBF changes attributable to emotion with subjects' scores on the Levels of Emotional Awareness Scale (LEAS), a measure of individual differences in the capacity to experience emotion in a differentiated and complex way. A conjunction analysis revealed that the correlations between LEAS and CBF during film- and recall-induced emotion overlapped significantly (z = 3.74, p < 0. 001) in Brodmann's area 24 of the anterior cingulate cortex (ACC). This finding suggests that individual differences in the ability to accurately detect emotional signals interoceptively or exteroceptively may at least in part be a function of the degree to which the ACC participates in the experiential processing and response to emotion cues. To the extent that this finding is consistent with the functions of the ACC involving attention and response selection, it suggests that this neural correlate of conscious emotional experience is not exclusive to emotion.
近期的功能成像研究已开始在健康志愿者中识别情绪的神经关联。然而，迄今为止的研究尚未分别探讨在情绪唤起期间与情绪感知、体验或表达相关的脑区。为了探究情绪体验的神经关联，我们使用正电子发射断层扫描（PET）和15水来测量12名健康女性在电影诱发和回忆诱发情绪期间的脑血流量（CBF），并将情绪引起的CBF变化与受试者在情绪意识量表（LEAS）上的得分相关联，LEAS是一种衡量个体以差异化和复杂方式体验情绪能力的个体差异指标。联合分析显示，在电影诱发和回忆诱发情绪期间，LEAS与CBF之间的相关性在前扣带回皮质（ACC）的布罗德曼24区显著重叠（z = 3.74，p < 0.001）。这一发现表明，个体在通过内感受或外感受准确检测情绪信号能力上的差异可能至少部分取决于ACC参与情绪线索体验处理和反应的程度。就这一发现与ACC涉及注意力和反应选择的功能一致而言，它表明这种有意识情绪体验的神经关联并非情绪所独有。
