Dang Qinpu, Ma Fengyang, Chen Jingyu, Guo Taomei
State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
School of Psychological and Cognitive Sciences, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.
Brain Struct Funct. 2025 Jun 10;230(6):95. doi: 10.1007/s00429-025-02955-z.
In the present research, we examined the neural substrates associated with positive word processing by using Activation Likelihood Estimation (ALE) and Seed-based d Mapping (SDM) approaches. In study 1, taking effect sizes, peak coordinates of brain region activation, sample sizes, and experimental paradigms into consideration in ALE and SDM meta-analyses, we identified two largely overlapping brain regions with comparable peak coordinates, i.e., the left medial prefrontal cortex (mPFC) and the left posterior cingulate cortex (PCC), showing greater activities in these two regions during positive word processing than neutral word processing. In Study 2, we further examined the universality and language specificity of neural mechanisms underlying positive word processing by comparing two typologically distant languages, Chinese and English, in both native speakers and bilinguals using ROI (regions of interest) analyses. The results showed no significant difference across two native languages or between bilinguals' two languages, highlighting the universal role of the two regions in positive word processing. These findings also hold implications for the models of bilingual emotion processing (e.g., the valence hypothesis and the hierarchical emotion model) and the system accommodation hypothesis.
在本研究中，我们使用激活可能性估计（ALE）和基于种子点的映射（SDM）方法，研究了与积极词汇加工相关的神经基础。在研究1中，在ALE和SDM元分析中考虑效应量、脑区激活的峰值坐标、样本量和实验范式后，我们确定了两个在很大程度上重叠且峰值坐标相当的脑区，即左侧内侧前额叶皮质（mPFC）和左侧后扣带回皮质（PCC），在积极词汇加工过程中，这两个区域的活动比中性词汇加工时更强烈。在研究2中，我们通过使用感兴趣区（ROI）分析，比较了两种类型差异较大的语言（中文和英文）的母语者和双语者，进一步研究了积极词汇加工背后神经机制的普遍性和语言特异性。结果显示，在两种母语之间或双语者的两种语言之间均无显著差异，突出了这两个区域在积极词汇加工中的普遍作用。这些发现也对双语情绪加工模型（如效价假设和层次情绪模型）以及系统适应假设具有启示意义。
