法国南部淡色库蚊中与有机磷抗性相关的Est-2和Est-3多态性

Est-2 and Est-3 polymorphisms in Culex pipiens L. from Southern France in relation to organophosphate resistance.

作者信息

Pasteur N, Sinègre G, Gabinaud A

出版信息

Biochem Genet. 1981 Jun;19(5-6):499-508. doi: 10.1007/BF00484622.

DOI:10.1007/BF00484622

Abstract

Est-2 and Est-3 linkage disequilibrium was investigated in 43 natural populations. An association between Est-2(0.64) and Est-3A alleles (or its reverse, Est-3Null and alleles other than Est-2(0.64) was not observed in 19 (1.2%) of the 1599 mosquitoes analyzed, whereas it should have been found in nearly 400 (25%) individuals if the two loci were in equilibrium. This observation is discussed in relation to organophosphate resistance and genetic distance of the two genes.

摘要

在43个自然种群中研究了Est-2和Est-3的连锁不平衡。在分析的1599只蚊子中，有19只（1.2%）未观察到Est-2(0.64)与Est-3A等位基因之间的关联（或者相反，Est-3Null与Est-2(0.64)以外的等位基因之间的关联），而如果这两个基因座处于平衡状态，预计在近400只（25%）个体中会发现这种关联。结合有机磷抗性和这两个基因的遗传距离对这一观察结果进行了讨论。

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