Symon D N
Department of Paediatrics, Hartlepool General Hospital, Cleveland, UK.
Arch Dis Child. 1998 Jun;78(6):555-6. doi: 10.1136/adc.78.6.555.
Analgesic headache occurs when drugs given for the treatment of headache aggravate symptoms. The condition is well recognised in adults but has not been described before in children in whom it may be induced by mild analgesics such as paracetamol used alone. Twelve children (nine girls and three boys, aged 6 to 16.5 years) with analgesic headache (from three months to 10 years) are reported. Five children were taking paracetamol alone, six were taking paracetamol with codeine, and one child was taking ibuprofen. The abrupt withdrawal of analgesic drugs was successful in eight of the children; two had episodic migraine headaches; one had headaches but with reduced frequency; and one returned to analgesic abuse.
止痛药物性头痛是指用于治疗头痛的药物反而加重症状的情况。这种情况在成人中已得到充分认识,但此前在儿童中尚未有过描述,儿童中它可能由单独使用的对乙酰氨基酚等轻度镇痛药诱发。本文报告了12例(9名女孩和3名男孩,年龄6至16.5岁)患有止痛药物性头痛(病程3个月至10年)的儿童。5名儿童单独服用对乙酰氨基酚,6名儿童服用对乙酰氨基酚加可待因,1名儿童服用布洛芬。8名儿童成功停用了止痛药物;2名患有发作性偏头痛;1名仍有头痛但发作频率降低;1名又恢复了滥用止痛药物的行为。