Arif M, Ramia S
Department of Pathology (32), College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ann Trop Med Parasitol. 1998 Apr;92(3):305-9. doi: 10.1080/00034989859870.
During the past 6 years, blood donors at various hospitals and blood banks in Saudi Arabia have been screened by enzyme immuno-assay for antibodies to human T-lymphotropic virus type I (anti-HTLV-I). Seropositivity for anti-HTLV-I, clearly confirmed by western blot, was only demonstrable in three out of the 34,541 subjects (including at least 21,000 Saudi nationals). The three positives were all expatriates: two Indians and one Syrian. Another six subjects, who gave ambiguous reactions on western blots and may also have been positive, were also all expatriates. Saudi Arabia therefore appears to be a non-endemic area for HTLV-I and hence the current practice of screening all blood donors for anti-HTLV-I does not seem to be cost-effective. An alternative strategy, in which only expatriate blood donors are screened, should perhaps be considered by the Saudi Ministry of Health.
在过去6年里，沙特阿拉伯各医院和血库的献血者都接受了酶免疫测定，以检测抗人类嗜T淋巴细胞病毒I型抗体（抗-HTLV-I）。经蛋白质印迹法明确证实，在34541名受试者中（包括至少21000名沙特国民），只有3人抗-HTLV-I血清呈阳性。这3名阳性者均为外籍人士：2名印度人，1名叙利亚人。另外6名在蛋白质印迹法检测中反应不明确、可能也呈阳性的受试者也都是外籍人士。因此，沙特阿拉伯似乎是HTLV-I的非流行区，所以目前对所有献血者进行抗-HTLV-I筛查的做法似乎并不具有成本效益。沙特卫生部或许应考虑另一种策略，即只对外籍献血者进行筛查。
