Balkhy Hanan H, Memish Ziad A, Abed Eman, Qasem Laila, Amer Amal Bin, Masoud Soha, Hajeer Ali H
Department of Pediatrics, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
Mil Med. 2004 Mar;169(3):251-3. doi: 10.7205/milmed.169.3.251.
Human T cell lymphotropic virus (HTLV) I/II is a retrovirus that is usually transmitted through transfusion of cellular blood products, sexual contact, and vertically from mother to child through breastfeeding. Policies to screen donated blood for this virus have varied from country to country, based on seroepidemiological data. Before 1991, no such data existed on HTLV-I/II among the Saudi population. Since then, several reports have documented a low seroprevalence rate among Saudi blood donors (0-0.026%). We did a retrospective review of all blood donated at King Fahad National Guard Hospital over the preceding 3 years to assess the seroprevalence of HTLV-I/II. After retesting positive and borderline samples, we were able to detect 1 positive and 38 borderline samples. As well, we reviewed the Saudi literature to identify the national seroprevalence of the disease and propose a cost-effective approach for screening donated blood in Saudi Arabia for HTLV-I/II.
人类嗜T淋巴细胞病毒（HTLV）I/II是一种逆转录病毒，通常通过输注细胞血液制品、性接触以及母婴在母乳喂养时垂直传播。基于血清流行病学数据，各国针对该病毒筛查献血的政策各不相同。1991年之前，沙特人群中尚无关于HTLV-I/II的此类数据。自那时起，几份报告记录了沙特献血者中较低的血清阳性率（0-0.026%）。我们对法赫德国民警卫队医院在过去3年所献的所有血液进行了回顾性审查，以评估HTLV-I/II的血清阳性率。在对阳性和临界样本进行重新检测后，我们检测到1份阳性样本和38份临界样本。此外，我们查阅了沙特的文献，以确定该国该疾病的血清阳性率，并提出一种经济有效的方法用于在沙特阿拉伯筛查献血中的HTLV-I/II。
