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先天性青光眼小梁切除术的长期效果

Long-term results of trabeculectomy for congenital glaucoma.

作者信息

Dureau P, Dollfus H, Cassegrain C, Dufier J L

机构信息

Institution Service d'Ophtalmologie, Hôpital Necker-Enfants Malades, Université René Descartes, Paris, France.

出版信息

J Pediatr Ophthalmol Strabismus. 1998 Jul-Aug;35(4):198-202. doi: 10.3928/0191-3913-19980701-05.

Abstract

BACKGROUND

To evaluate long-term results of intraocular pressure after trabeculectomy for congenital glaucoma.

METHODS

Data concerning 55 eyes (30 patients) who underwent trabeculectomy for congenital glaucoma were recorded. Mean age at diagnosis was 3.4 months (range: 2 days to 10 months). Mean follow up was 56.8 months. Associated anterior segment abnormalities, need for one or more new trabeculectomy procedures during follow up, and intraocular pressure at the last examination were noted.

RESULTS

Of the 55 eyes, 48 met the success criteria (87.3%). A second and sometimes third or fourth trabeculectomy were necessary during follow up in 17 eyes (31%). Of the seven failures at final examination, six (85%) had been diagnosed and operated on before the age of 1 month, whereas 15 of the 48 eyes with good results (31.2%) were in this group (p < 0.02). Of the seven failures at final examination, six (85%) were operated on two to four times, whereas 10 of the 48 eyes with good results (20.1%) were in this group (p < 0.01). An associated anterior segment abnormality was present in 13 eyes (23%), and did not seem to influence the final outcome.

CONCLUSION

Trabeculectomy is an effective procedure for long-term control of intraocular pressure in congenital glaucoma. The early diagnosis and surgical treatment correspond to a poor long-term prognosis, probably related to initially severe cases. In these cases, intraocular pressure is difficult to control despite repeated surgical procedures.

摘要

背景

评估先天性青光眼小梁切除术后眼压的长期结果。

方法

记录了55只眼(30例患者)行先天性青光眼小梁切除术的数据。诊断时的平均年龄为3.4个月(范围:2天至10个月)。平均随访时间为56.8个月。记录相关眼前段异常情况、随访期间是否需要进行一次或多次新的小梁切除手术以及最后一次检查时的眼压。

结果

55只眼中,48只(87.3%)符合成功标准。随访期间,17只眼(31%)需要进行第二次,有时是第三次或第四次小梁切除手术。最后检查的7只失败眼中,6只(85%)在1个月龄前被诊断并接受手术,而48只效果良好的眼中有15只(31.2%)属于该组(p<0.02)。最后检查的7只失败眼中,6只(85%)接受了两到四次手术,而48只效果良好的眼中有10只(20.1%)属于该组(p<0.01)。13只眼(23%)存在相关眼前段异常,似乎不影响最终结果。

结论

小梁切除术是长期控制先天性青光眼眼压的有效方法。早期诊断和手术治疗对应的长期预后较差,可能与最初病情严重有关。在这些病例中,尽管多次进行手术,眼压仍难以控制。

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