Huang Hailong, Bao Wenjun J, Yamamoto Tetsuya, Kawase Kazuhide, Sawada Akira
Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan,
Clin Ophthalmol. 2018 Dec 17;13:1-7. doi: 10.2147/OPTH.S186929. eCollection 2019.
To investigate the long-term postoperative outcome of three surgical procedures for childhood glaucoma.
In this retrospective study, the patients were divided into a goniotomy group, a trabeculotomy group, and a filtering surgery group, based on the initial surgical procedure. Failure was defined as an IOP ≥21 mmHg with medication at two consecutive visits. A Kaplan-Meier analysis was applied to calculate the probability of success. Additional metrics included IOP, number of additional operations, eye drop scores, and visual acuity.
We studied 40 eyes of 25 patients, 21 eyes of 15 patients, and 12 eyes of 7 patients in the goniotomy, trabeculotomy, and filtering surgery groups, respectively. The 10- and 20-year probability of success was 65.2% and 65.2%, 42.2% and NA (no data for 20 years), and 91.7% and 80.2% for the goniotomy, trabeculotomy, and filtering surgery groups, respectively.
All three procedures maintained an IOP of less than 21 mmHg for up to 10 years in 65.2%, 42.2%, and 91.7% of childhood glaucoma cases.
探讨三种儿童青光眼手术的术后长期疗效。
在这项回顾性研究中,根据初始手术方式将患者分为前房角切开术组、小梁切开术组和滤过手术组。失败定义为连续两次就诊时使用药物情况下眼压≥21 mmHg。采用Kaplan-Meier分析计算成功概率。其他指标包括眼压、额外手术次数、眼药水评分和视力。
我们分别对前房角切开术组25例患者的40只眼、小梁切开术组15例患者的21只眼和滤过手术组7例患者的12只眼进行了研究。前房角切开术组、小梁切开术组和滤过手术组的10年和20年成功概率分别为65.2%和65.2%、42.2%和无(20年无数据)、91.7%和80.2%。
在65.2%、42.2%和91.7%的儿童青光眼病例中,这三种手术均能使眼压在长达10年内维持在21 mmHg以下。