Kafka M P, Prentky R A
Harvard Medical School, Boston, Mass, USA.
J Clin Psychiatry. 1998 Jul;59(7):388-96; quiz 397. doi: 10.4088/jcp.v59n0709.
We describe a study of DSM-III-R Axis I diagnoses of lifetime comorbid nonsexual disorders in 60 males with paraphilias (PAs; N = 42) and nonparaphilic forms of sexual impulsivity-designated paraphilia-related disorders (PRD; N = 18).
Subjects completed a semistructured intake questionnaire and sexual inventories, the Inventory to Diagnose Depression, and the Wender Utah Retrospective Scale for the diagnosis of childhood attention-deficit/hyperactivity disorder (ADHD). The lifetime prevalence of Axis I diagnoses of both sexual and nonsexual disorders was ascertained from the aforementioned data and follow-up psychiatric interviews.
Subjects in both PA and PRD groups were diagnosed as having a lifetime prevalence of any mood disorder (71.7%), especially dysthymic disorder (66.7%); any anxiety disorder (43.3%), especially social phobia (28.3%); any psychoactive substance abuse disorders (45.0%), especially alcohol abuse (30.0%); and any impulse disorders NOS (25.0%), especially speeding/reckless driving (16.7%). The only diagnosis that statistically significantly distinguished the PA from the PRD sample (p = .01) was retrospectively diagnosed childhood ADHD, identified in 40.0% of the total sample (50.0% PA vs.16.7% PRD). Childhood ADHD was associated with the presence of educational and behavioral problems, lower current mean income, social/legal consequences associated with antisocial impulsivity, cocaine abuse, increased prevalence of comorbid lifetime mood and impulse disorder NOS, and more diagnoses of lifetime Axis I nonsexual and sexual disorders.
Although depressive disorders were the most common Axis I diagnoses across groups, childhood ADHD was the only Axis I disorder statistically significantly associated with paraphilias, socially deviant and aggressive forms of sexual impulsivity.
我们描述了一项针对60名患有性偏好障碍(PA;N = 42)和非性偏好障碍形式的性冲动——指定为性偏好障碍相关障碍(PRD;N = 18)的男性一生中共病的非性障碍的DSM-III-R轴I诊断研究。
受试者完成了一份半结构化的入院调查问卷、性清单、诊断抑郁症量表以及用于诊断儿童注意力缺陷多动障碍(ADHD)的温德犹他回顾性量表。从上述数据和后续的精神科访谈中确定轴I诊断的性和非性障碍的终生患病率。
PA组和PRD组的受试者均被诊断为终生患任何情绪障碍的患病率为71.7%,尤其是恶劣心境障碍(66.7%);任何焦虑障碍的患病率为43.3%,尤其是社交恐惧症(28.3%);任何精神活性物质滥用障碍的患病率为45.0%,尤其是酒精滥用(30.0%);以及任何未特定的冲动障碍的患病率为25.0%,尤其是超速/鲁莽驾驶(16.7%)。唯一在统计学上能显著区分PA组和PRD组样本的诊断(p = .01)是回顾性诊断的儿童ADHD,在总样本的40.0%中被发现(PA组为50.0%,PRD组为16.7%)。儿童ADHD与教育和行为问题的存在、当前平均收入较低、与反社会冲动相关的社会/法律后果、可卡因滥用、共病终生情绪和未特定的冲动障碍患病率增加以及更多的终生轴I非性和性障碍诊断相关。
尽管抑郁症是各组中最常见的轴I诊断,但儿童ADHD是唯一在统计学上与性偏好障碍、社会偏差和攻击性形式的性冲动显著相关的轴I障碍。