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依替卡因与利多卡因用于产科镇痛的比较。

Comparison of etidocaine and lidocaine for obstetrical analgesia.

作者信息

Edelist G, Perera E

出版信息

Can Anaesth Soc J. 1976 Sep;23(5):459-64. doi: 10.1007/BF03005974.

Abstract

Etidocaine, a relatively new local anaesthetic agent, is compared with lidocaine for use in epidural anaesthesia for vaginal delivery. The parameters compared were quality of anaesthesia, dose of drug, onset and regression of sensory blockade, complete degree of motor blockade, effect on maternal blood pressure, and foetal Apgar scores at one and five minutes. The major differences between the drugs are the lower percentage of satisfactory anaesthesia with etidocaine, the much greater variability in the time of onset of complete sensory block with etidocaine as compared to lidocaine, the more profound motor block with etidocaine, and the slightly longer duration of action of this drug. It is concluded that etidocaine has no real place in epidural anaesthesia for obstetrics.

摘要

依替卡因是一种相对较新的局部麻醉剂,本文将其与利多卡因用于阴道分娩的硬膜外麻醉进行比较。比较的参数包括麻醉质量、药物剂量、感觉阻滞的起效和消退时间、运动阻滞的完全程度、对产妇血压的影响以及胎儿1分钟和5分钟时的阿氏评分。两种药物的主要差异在于,依替卡因麻醉效果满意的比例较低,与利多卡因相比,依替卡因完全感觉阻滞的起效时间差异大得多,依替卡因运动阻滞更明显,且该药作用持续时间略长。结论是,依替卡因在产科硬膜外麻醉中并无实际应用价值。

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