Brogniez V, Lejuste P, Pecheur A, Reychler H
Department of Prosthodontics, Catholic University of Louvain, Bruxelles, Belgium.
Int J Oral Maxillofac Implants. 1998 Jul-Aug;13(4):506-12.
Nineteen patients who were treated for oncologic pathology by surgery and radiotherapy (average dose = 57 Gy) received prosthetic reconstruction with 53 implants placed in the residual mandible or maxilla and/or replacement bone graft. Implants were placed within a minimum period of 5 months after radiotherapy. The healing period before placement of the prosthesis also was at least 5 months. Two to six implants were placed as a function of tooth loss and required prosthetic design. Prostheses included both removable and fixed restorations. Two implants were lost as a result of osseointegration failure. Fifteen implants in six patients could not be followed throughout the study because of patient expiration. Patients were followed up to 68 months and for an average of 38 months. No osteoradionecrosis phenomenon was seen in this study. However, caution is urged in placing implants in irradiated bone because of the potential for osteoradionecrosis. Patients should be carefully selected and a strict therapeutic protocol should be followed.
19名接受手术和放疗（平均剂量=57 Gy）治疗肿瘤病理的患者接受了假体重建，在残余下颌骨或上颌骨和/或替代骨移植中植入了53枚种植体。种植体在放疗后至少5个月内植入。假体植入前的愈合期也至少为5个月。根据牙齿缺失情况和所需的假体设计植入2至6枚种植体。假体包括可摘和固定修复体。2枚种植体因骨整合失败而丢失。由于患者死亡，6名患者中的15枚种植体在整个研究过程中无法追踪。对患者进行了长达68个月的随访，平均随访38个月。本研究中未观察到放射性骨坏死现象。然而，由于存在放射性骨坏死的可能性，在照射过的骨中植入种植体时应谨慎。应仔细选择患者，并遵循严格的治疗方案。
