Esser E, Wagner W
Department of Maxillo-Facial Surgery, Städtische Kliniken, Osnabrück, Germany.
Int J Oral Maxillofac Implants. 1997 Jul-Aug;12(4):552-7.
Following radical oral cancer surgery and postoperative adjuvant radiotherapy with a total dose of 60 Gy, 71 IMZ and 150 Brånemark implants were placed in the mandibles and 28 Brånemark implants were placed in the maxillas of 60 patients between 1985 and 1995. Adjunctive hyperbaric oxygen therapy was not used. Osteoradionecrosis of the mandible occurred in two patients (3.4%), and necrosis of soft tissue in the floor of the mouth region occurred in three patients (5.2%). Twenty-one implants (18 in the mandible and 2 in the maxilla) were not osseointegrated when surgically exposed. In subsequent follow-up, 17 mandibular implants and 5 maxillary implants lost their osseointegration. The life table method indicated that 5-year actuarial implant success rates in the irradiated mandible were 77.5% for the IMZ system and 83.6% for the Brånemark system. These differences were not statistically significant. Retrospective analysis indicated that the success of implants in the irradiated mandible is determined after an interval of 18 to 24 months. For a small number of Brånemark implants in the irradiated maxilla, an actuarial success rate of 85.5% was found.
1985年至1995年间，60例患者在接受口腔癌根治性手术后接受了总量为60 Gy的术后辅助放疗，在下颌骨植入了71枚IMZ种植体和150枚Brånemark种植体，在上颌骨植入了28枚Brånemark种植体。未采用辅助高压氧治疗。2例患者（3.4%）发生下颌骨放射性骨坏死，3例患者（5.2%）发生口底软组织坏死。手术暴露时，有21枚种植体（下颌骨18枚，上颌骨2枚）未实现骨整合。在随后的随访中，17枚下颌种植体和5枚上颌种植体失去了骨整合。生命表法显示，照射后下颌骨中IMZ系统的5年精算种植成功率为77.5%，Brånemark系统为83.6%。这些差异无统计学意义。回顾性分析表明，照射后下颌骨种植体的成功在18至24个月的间隔后确定。对于照射后上颌骨中的少量Brånemark种植体，精算成功率为85.5%。
