Ewing F M, Deary I J, Strachan M W, Frier B M
Department of Diabetes, Royal Infirmary of Edinburgh, United Kingdom.
Endocr Rev. 1998 Aug;19(4):462-76. doi: 10.1210/edrv.19.4.0340.
Contrast sensitivity testing, in common with color vision (another test of psychophysical function), demonstrates significant changes in diabetic subjects compared with nondiabetic controls, and there is some evidence for a relationship with grade of retinopathy. Changes in contrast sensitivity have been demonstrated in children and adults with diabetes of short duration, and some evidence exists for a correlation with poor glycemic control, although prospective studies are required to assess this relationship over a longer time period. Although both color vision and contrast sensitivity demonstrate similar patterns, studies that directly compare the two tests suggest that measurement of contrast sensitivity is the more sensitive and specific.
与色觉(心理物理功能的另一项测试)一样,对比敏感度测试表明,与非糖尿病对照组相比,糖尿病患者有显著变化,并且有一些证据表明其与视网膜病变程度有关。对比敏感度的变化已在病程较短的糖尿病儿童和成人中得到证实,并且有一些证据表明其与血糖控制不佳相关,不过需要前瞻性研究来在更长时间段内评估这种关系。尽管色觉和对比敏感度都呈现出相似模式,但直接比较这两项测试的研究表明,对比敏感度测量更为敏感和特异。