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[母婴由疣状毛癣菌引起的皮肤真菌病]

[Dermatomycosis caused by Trichophyton verrucosum in mother and child].

作者信息

Czaika V, Tietz H J, Schulze P, Sterry W

机构信息

Dermatologische Universitätsklinik und Poliklinik, Medizinischen Fakultät (Charité), Humboldt-Universität zu Berlin.

出版信息

Hautarzt. 1998 Jul;49(7):576-80. doi: 10.1007/s001050050792.

Abstract

In recent years, there has been an epidemiological renaissance of zoophilic dermatophytoses caused by a variety of factors. At present, the most important causative organisms are Microsporum canis, Trichophyton mentagrophytes var. granulosum and, as in the present case, Trichophyton verrucosum. These are formerly notifiable pathogens which are highly virulent and contagious. The example of an extensive, originally unrecognized tinea corporis et faciei in mother and child presented here shows the current importance of Trichophyton verrucosum, but also the diagnostic difficulties in dealing with a formerly rare infection disease. The inflammatory symptoms of deep trichophytosis with imminent danger of scar formation was the basis of synergistic combination therapy in the two patients. The source of infection for zoophilic dermatomycosis at the beginning of the epidemiological increase were looked for almost exclusively in Mediterranean countries. However, there are now increased indications of indigenous pools. In view of the neglect of consistent immunization of livestock and the lack of a requirement to notify the disease, a further rise in the number of cases in humans is to be expected.

摘要

近年来,由于多种因素,亲动物性皮肤癣菌病出现了流行病学复兴。目前,最重要的致病生物是犬小孢子菌、须癣毛癣菌颗粒变种,以及如本例中的疣状毛癣菌。这些以前都是应报告的病原体,具有高度毒性和传染性。这里展示的母婴广泛、最初未被识别的体癣和面癣病例,表明了疣状毛癣菌目前的重要性,也显示了处理一种以前罕见的传染病时的诊断困难。两名患者深部皮肤癣菌病伴有即将形成瘢痕的炎症症状,是联合协同治疗的基础。在流行病学增加初期,亲动物性皮肤真菌病的感染源几乎完全在地中海国家被寻找。然而,现在越来越多地表明存在本地疫源地。鉴于对牲畜持续免疫的忽视以及缺乏疾病报告要求,预计人类病例数将进一步上升。

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