Potério M B, Alves M R, Cardillo J A, José N K
Department of Ophthalmology, UNICAMP School of Medicine, Campinas-SP, Brazil.
Ophthalmic Surg Lasers. 1998 Aug;29(8):685-7.
A surgical technique was designed to improve safety after pterygium excision with intraoperative application of mitomycin-C (MMC). A limbic incision was performed in 40 eyes. The body of the pterygium was dissected from the episclera to allow its excision. Care was taken to avoid excessive delamination and cauterization of tissues. A 0.02% MMC solution was then applied. Only at the end of the surgery was the head of the pterygium dissected from the cornea. The 8-0 absorbable sutures were used to place both edges of the conjunctiva together to completely cover the area of bare sclera. After a mean follow-up time of 12 months, a recurrence rate of 5% was observed. No complications of therapy were observed. This is a logical alternative to other surgical techniques. However, randomized studies with more patients and longer follow-up are necessary to determine the potential of this procedure in improving the safety of pterygium excision with intraoperative MMC.
设计了一种手术技术,通过术中应用丝裂霉素-C(MMC)来提高翼状胬肉切除术后的安全性。对40只眼进行了角膜缘切口。将翼状胬肉的主体从巩膜表面分离以便切除。注意避免组织过度分层和烧灼。然后应用0.02%的MMC溶液。仅在手术结束时才将翼状胬肉的头部从角膜上分离。使用8-0可吸收缝线将结膜的两边缝合在一起,以完全覆盖裸露的巩膜区域。平均随访12个月后,观察到复发率为5%。未观察到治疗并发症。这是其他手术技术的合理替代方法。然而,需要更多患者参与且随访时间更长的随机研究,以确定该手术在提高术中应用MMC进行翼状胬肉切除安全性方面的潜力。