Nielsen J B, Grandjean P, Jørgensen P J
Odense Universitet, Afdeling for Miljømedicin.
Ugeskr Laeger. 1998 Aug 10;160(33):4768-71.
Blood lead concentrations in a Danish reference population were related to information from an extensive questionnaire on work, environment and life style. The mean concentration of lead in blood was 0.167 mumol/L, i.e. significantly lower than in previous studies. This finding is in accordance with the fact that less than 10% of petrol used in Denmark contained lead additives (up to 0.15 g/L). An important finding was that the well-documented predictors for lead in blood at higher concentration levels, such as age, gender, menopausal status, and intake of alcohol, are still valid in a low-level exposure situation. In addition, a strong and negative correlation was found between blood lead concentrations and dietary supplementation with vitamins and minerals. The present data indicate that lead exposure may still constitute a health risk in a small proportion of adult males and postmenopausal women.
丹麦参考人群的血铅浓度与一份关于工作、环境和生活方式的详尽调查问卷所提供的信息相关。血铅的平均浓度为0.167微摩尔/升,即显著低于先前的研究结果。这一发现与丹麦使用的汽油中含铅添加剂(最高0.15克/升)不到10%这一事实相符。一项重要发现是,在高浓度血铅水平下已得到充分证明的预测因素,如年龄、性别、绝经状态和酒精摄入量,在低水平接触情况下仍然有效。此外,还发现血铅浓度与维生素和矿物质的膳食补充剂之间存在强烈的负相关。目前的数据表明,铅暴露在一小部分成年男性和绝经后女性中可能仍然构成健康风险。