脐带血与骨髓及外周血中干细胞的计数
Stem cell enumeration in cord blood vs bone marrow and peripheral blood.
作者信息
Bertolini F, Battaglia M, Lanza A, Gibelli N, Palermo B, Pavesi L, Robustelli della Cuna G
机构信息
Division of Medical Oncology and Experimental Medicine, IRCCS Maugeri Foundation, Pavia Medical Center, Italy.
出版信息
Bone Marrow Transplant. 1998 Jul;22 Suppl 1:S57.
PMID:9715890
Abstract
Recent reports have suggested that the total number of autologous or allogeneic hematopoietic stem cell (HSC) infused after high-dose chemotherapy might predict survival, post-transplant morbidity and rate of hematopoietic engraftment. However, HSC capable of long-term multilineage potential are still poorly defined, and tools for accurate and reproducible HSC enumeration are highly warranted.
摘要
最近的报告表明，大剂量化疗后输注的自体或异基因造血干细胞（HSC）总数可能预测生存率、移植后发病率和造血植入率。然而，具有长期多谱系潜能的HSC仍定义不清，因此非常需要能够准确且可重复地计数HSC的工具。
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