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原发性无反流巨输尿管是否需要手术治疗?

Is surgery necessary for primary non-refluxing megaureter?

作者信息

Sheu J C, Chang P Y, Wang N L, Tsai T C, Huang F Y

机构信息

Department of Pediatric Surgery, Mackay Memorial Hospital, 92, Sec. 2, Chung San N. Road, Taipei, Taiwan, Republic of China.

出版信息

Pediatr Surg Int. 1998 Sep;13(7):501-3. doi: 10.1007/s003830050383.

Abstract

From January 1990 to December 1995, a total of 22 patients with primary non-refluxing megaureter were treated in our hospital. The age distribution was 7 days to 8 years. The follow-up period was from 1 to 6 years. Nineteen of these 22 children underwent surgical intervention: 3 were operated upon at the time of diagnosis; the other 16 were initially treated conservatively, but underwent subsequent surgery due to impairment of renal function (13) or breakthrough infections (3). The failure rate for conservative management was about 84% (16/19): only 3 patients treated conservatively showed spontaneous resolution. The surgical success rate was 89.5% (17/19). The pathological change in the ureterovesical junction (UVJ) was adynamic in 13 cases and fibrotic in 6 (including 1 ectopic ureter). The postoperative complications were vesicoureteric reflux in 3 cases, with spontaneous resolution 6 months later, and UVJ stenosis in 1, which was resolved by reoperation. It is concluded that surgery is not necessary in every case, but still plays an important role in most cases. Early surgery can achieve good results and reduce renal damage.

摘要

1990年1月至1995年12月,我院共收治22例原发性无反流巨输尿管患者。年龄分布为7天至8岁。随访时间为1至6年。这22例患儿中,19例接受了手术干预:3例在诊断时即接受手术;另外16例最初采用保守治疗,但因肾功能损害(13例)或反复感染(3例)而接受了后续手术。保守治疗的失败率约为84%(16/19):仅3例保守治疗患者显示自行缓解。手术成功率为89.5%(17/19)。输尿管膀胱连接部(UVJ)的病理改变中,13例为动力性缺失,6例为纤维化(包括1例异位输尿管)。术后并发症包括3例膀胱输尿管反流,6个月后自行缓解,1例UVJ狭窄,通过再次手术得以解决。结论是,并非所有病例都需要手术,但在大多数情况下手术仍起着重要作用。早期手术可取得良好效果并减少肾脏损害。

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