van Domburg R T, Klootwijk P, Deckers J W, van Bergen P F, Jonker J J, Simoons M L
Thoraxcenter, Erasmus University, Rotterdam, The Netherlands.
Eur Heart J. 1998 Jul;19(7):1034-41. doi: 10.1053/euhj.1998.1011.
The Cardiac Infarction Injury Score (CIIS) is an electrocardiographic classification system that was developed as a diagnostic tool to assess the extent of cardiac injury in acute myocardial infarction. We investigated the prognostic value of the CIIS in post-myocardial infarction patients.
The prognostic values of the CIIS for total and cardiac mortality was assessed in a large series (n = 3395) of patients who were enrolled in the ASPECT trial. Standard 12-lead electrocardiograms, recorded prior to hospital discharge were coded according to the CIIS and the Minnesota Code. Mean CIIS was 26 (range--8 to 59). After adjustment for other baseline characteristics, the CIIS was directly related to the risk of total mortality and cardiac mortality. At one-year follow-up the relative risks of CIIS > or = 40, CIIS 30-40 and CIIS 20-30 were significantly higher than in those with a CIIS < 20. The relative risks were, respectively, 2.3 (1.2-4.4), 2.2 (1.3-3.9) and 1.6 (0.9-2.9). At 3 year follow-up, the relative risks were, respectively, 2.1 (1.4-3.2), 1.7 (1.2-2.4) and 1.5 (1.0-2.1). The relative risks for total mortality were similar. When patients with major ECG abnormalities, as defined by the Minnesota code, were excluded, the associations were still significant in the CIIS classes 30-40 and > 40.
The CIIS ECG scoring system is an important predictor for long-term cardiac mortality in post myocardial infarction patients. It can easily be automated and is efficient for classifying cardiac injury in epidemiological studies.
心肌梗死损伤评分（CIIS）是一种心电图分类系统，作为诊断工具用于评估急性心肌梗死中心脏损伤的程度。我们研究了CIIS在心肌梗死后患者中的预后价值。
在纳入ASPECT试验的一大组患者（n = 3395）中评估CIIS对全因死亡率和心脏死亡率的预后价值。出院前记录的标准12导联心电图根据CIIS和明尼苏达编码进行编码。CIIS的平均值为26（范围为 - 8至59）。在对其他基线特征进行调整后，CIIS与全因死亡率和心脏死亡率风险直接相关。在一年随访时，CIIS≥40、CIIS 30 - 40和CIIS 20 - 30的相对风险显著高于CIIS < 20的患者。相对风险分别为2.3（1.2 - 4.4）、2.2（1.3 - 3.9）和1.6（0.9 - 2.9）。在3年随访时，相对风险分别为2.1（1.4 - 3.2）、1.7（1.2 - 2.4）和1.5（1.0 - 2.1）。全因死亡率的相对风险相似。当排除明尼苏达编码定义的主要心电图异常患者时，CIIS 30 - 40和> 40组中的关联仍然显著。
CIIS心电图评分系统是心肌梗死后患者长期心脏死亡率的重要预测指标。它易于自动化，在流行病学研究中对心脏损伤进行分类很有效。
