Hatt J M, Sainsbury A W
Department of Zoo Animals and Exotic Pets, Faculty of Veterinary Medicine, University of Zurich, Switzerland.
Vet Rec. 1998 Jul 18;143(3):78-80. doi: 10.1136/vr.143.3.78.
Metabolic bone disease was diagnosed in an 11-month-old female common marmoset (Callithrix jacchus). It was depressed, reluctant to move, and was cachectic and small for its age. Laboratory findings included anaemia, azotaemia and an inverse calcium to phosphorus ratio. The radiological findings showed simultaneous signs of osteomalacia and soft-tissue calcification. There was decreased bone density with lytic areas in the pelvis and femur, and severe bilateral nephrocalcinosis. Postmortem examination revealed marked focal dystrophic calcification of the epi- and myocardium. Calcium and vitamin D3 deficiency (nutritional secondary hyperparathyroidism) was the most likely cause of the osteomalacia.
一只11个月大的雌性普通狨猴（绢毛猴）被诊断出患有代谢性骨病。它精神萎靡，不愿活动，身体消瘦，相对于其年龄来说体型较小。实验室检查结果包括贫血、氮血症以及钙磷比值倒置。放射学检查结果显示同时存在骨软化和软组织钙化的迹象。骨盆和股骨的骨密度降低，出现溶骨区，并且双侧严重肾钙质沉着。尸检显示心外膜和心肌有明显的局灶性营养不良性钙化。钙和维生素D3缺乏（营养性继发性甲状旁腺功能亢进）很可能是骨软化的病因。
